Construction of Analogy-Based Research Programs, The: The Lock-And-Key Analogy in 20th Century Biochemistry

Construction of Analogy-Based Research Programs, The: The Lock-And-Key Analogy in 20th Century Biochemistry
Rebecca Mertens
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NZ$ 100.00
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NZ$ 85.00
Paperback
h226 x 147mm - 230pg
21 May 2019 AX
International import eta 10-30 days
9783837644425
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When the German chemist Emil Fischer presented his key-lock hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity. Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modeling.

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